Metab Pediatr Syst Ophthalmol 1989;12:80-2. A., Santizo, M. C., Lonnerdal, B., and Brown, K. H. Impact of zinc supplementation on morbidity from diarrhea and respiratory infections among rural Guatemalan children. Barrett S. Zicam Marketers Sued. Infant development. Altunbasak S, Biatmakoui F, Baytok V, et al. Am J Clin Nutr 1997;66:639-42. Jamilian M, Foroozanfard F, Bahmani F, Talaee R, Monavari M, Asemi Z. View abstract. Bonham M, O'Connor JM, Alexander HD, et al. Golik A, Modai D, Averbukh Z, et al. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Dooren JC. 2003;55(6):1143-1147. If you have questions about side effects, call your doctor. B., and Campa, A. Randomized, controlled clinical trial of zinc supplementation to prevent immunological failure in HIV-infected adults. Hepatology 2000;32(4 Pt 1):877. Am J Clin Nutr 1988;47:484-6. Khanna VJ, Shieh S, Benjamin J, et al. View abstract. Gulani, A. and Sachdev, H. S. Zinc supplements for preventing otitis media. The comparative clinical efficacy of pyrophosphate/triclosan, copolymer/triclosan and zinc citrate/triclosan dentifrices for the reduction of supragingival calculus formation. 2014 Oct;40(10):2110-3. Am.J.Ther. Bhutta, Z. Akhondzadeh S, Mohammadi MR, Khademi M. Zinc sulfate as an adjunct to methylphenidate for the treatment of attention deficit hyperactivity disorder in children :a double blind and randomized trial. View abstract. However, zinc does not appear to improve disease severity or recurrence. 6-18-1991;69(9):392-396. Ophthalmology 1999;106:761-77. JAMA 1998;279:1962-7. Desneves, K. J., Todorovic, B. E., Cassar, A., and Crowe, T. C. Treatment with supplementary arginine, vitamin C and zinc in patients with pressure ulcers: a randomised controlled trial. Higashi A, Ikeda T, Matsukura M, Matsuda I. Serum zinc and vitamin E concentrations in handicapped children treated with anticonvulsants. Br.J.Nutr. Katz RL, Keen CL, Litt IF, et al. View abstract. Dahl, H., Norskov, K., Peitersen, E., and Hilden, J. Zinc therapy of acetazolamide-induced side-effects. Int J Radiat.Oncol Biol Phys 2-1-2008;70(2):368-373. Int J Epidemiol. Zinc and immunity. View abstract. Two randomized controlled trials of zinc gluconate lozenge therapy of experimentally induced rhinovirus colds. The impact of zinc supplementation on Schistosoma mansoni reinfection rate and intensities: a randomized, controlled trial among rural Zimbabwean schoolchildren. Epidemiology 2002;13:38-44.. View abstract. PLoS One. Nutrition. Michaelsson G, Ljunghall K. Patients with dermatitis herpetiformis, acne, psoriasis and Darier's disease have low epidermal zinc concentrations. Wilkinson EAJ. Effect of intragastric pH on the absorption of oral zinc acetate and zinc oxide in young healthy volunteers. Mol Cell Biochem 1998;188:63-9. Taking zinc along with some antibiotics might decrease the effectiveness of some antibiotics. Invest Ophthalmol Vis Sci 1996;37:1225-35. Available at: https://hstat2.nlm.nih.gov/download/409812772438.html. Clin Pharmacol Ther 1987;42:42-4. 2016;12:CD005436. 2020:e14252. Castillo-Duran, C., Rodriguez, A., Venegas, G., Alvarez, P., and Icaza, G. Zinc supplementation and growth of infants born small for gestational age. The effects seem to be greater in people with low levels of zinc before treatment. Available at: https://books.nap.edu/books/0309063507/html/index.html. Arch Ophthalmol 2001;119:1439-52. Equivalent uptake of organic and inorganic zinc by monkey kidney fibroblasts, human intestinal epithelial cells, or perfused mouse intestine. View abstract. Am J Clin Nutr 1997;65:1803-9. View abstract. A zinc-containing compound, Polaprezinc, is effective for patients with taste disorders: randomized, double-blind, placebo-controlled, multi-center study. The Age-Related Eye Disease Study (AREDS) Research Group. Controlled trial of D-penicillamine in rheumatoid arthritis. National Institutes of Health "Dietary supplement fact sheet: zinc. Svatun B, Saxton CA, Huntington E, Cummins D. The effects of a silica dentifrice containing Triclosan and zinc citrate on supragingival plaque and calculus formation and the control of gingivitis. Age-Related Eye Disease Study Research Group. Mahmoud AM, Al-Alem U, Dabbous F, et al. Also, some research suggests that taking zinc with vitamin A reduces the risk for some infections. Clin Immunol.Immunopathol. Rashidi, A. Low zinc intake seems to be linked to lower bone mass. View abstract. Grimwood, K. and Forbes, D. A. 2020;S0261-5614(20)30352-6. View abstract. 2007;47(3):216-221. George J, Bhatia VN, Balakrishnan S, Ramu G. Serum zinc/copper ratio in subtypes of leprosy and effect of oral zinc therapy on reactional states. Comparison of zinc concentrations in blood and seminal plasma and the various sperm parameters between fertile and infertile men. Reding, P., Duchateau, J., and Bataille, C. Oral zinc supplementation improves hepatic encephalopathy. View abstract. A., Sowa-Kucma, M., Zieba, A., Popik, P., Pilc, A., and Nowak, G. Zinc supplementation augments efficacy of imipramine in treatment resistant patients: a double blind, placebo-controlled study. J Nutr Biochem. 2004;18(3):137-141. Yee BE, Richards P, Sui JY, Marsch AF. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. A trial of zinc supplementation in young rural Gambian children. Scand.J.Plast.Reconstr.Surg. Ophthalmology. Varas Lorenzo, M. J., Lopez, Martinez A., Gordillo, Bernal J., and Mundet, Surroca J. View abstract. Zinc balance in adolescent females. View abstract. 1994 Feb;44(1 Suppl 1):75-81. Effect of ferrous sulfate and multivitamins with zinc on absorption of ciprofloxacin in normal volunteers. New York: Academic Press, 1976. Does intranasal application of zinc sulfate produce anosmia in the mouse? Valberg LS, Flanagan PR, Chamberlain MJ. Bleeding gastric erosion after oral zinc sulphate. VomitingWhen oral zinc is taken long term and in high doses it can cause copper deficiency. 5-13-1978;1(6122):1283-1284. Int.J Dermatol. Med Hypotheses 1985;17:157-65. 2016;61(1):78-84. Double-blind, randomized, controlled trial of zinc or vitamin A supplementation in young children with acute diarrhea. Nutr Metab Cardiovasc Dis. Quackwatch 2000. Microsc Res Tech 1993;24:195-213. Effect of routine zinc supplementation on pneumonia in children aged 6 months to 3 years: randomised controlled trial in an urban slum. Their effects are largely limited to throat and nasal symptoms, and high doses tend to come with some mild but notable side-effects like nausea and metallic taste in the mouth. View abstract. View abstract. Cochrane Database Syst Rev 2000;(2):CD001364. 2006;60(7):862-869. View abstract. Taking zinc by mouth does not seem to help treat IBD. BMC.Med 2009;7:22. Zinc in the human prostate gland: normal, hyperplastic and cancerous. Ead RD. View abstract. Available at: https://hc-sc.gc.ca/dhp-mps/alt_formats/pdf/medeff/advisories-avis/prof/2010/poligrip_hpc-cps-eng.pdf. A randomised controlled trial of oral zinc on the immune response to tuberculosis in HIV-infected patients. PLoS.One. 2016;83(4):289-93. Cereda, E., Gini, A., Pedrolli, C., and Vanotti, A. Disease-specific, versus standard, nutritional support for the treatment of pressure ulcers in institutionalized older adults: a randomized controlled trial. Liver scarring (cirrhosis). Mathur NK, Bumb RA, Mangal HN. 2017 Nov 21;11:CD011144. View abstract. View abstract. View abstract. Early research shows that taking zinc does not reduce tiredness or improve quality of life in people with colorectal cancer receiving chemotherapy. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E and beta carotene for age-related cataract and vision loss: AREDS report no. Med J Aust. Hillstrom L, Pettersson L, Hellbe L, et al. Int J Dermatol. View abstract. Sturniolo GC, Montino MC, Rossetto L, et al. Effect of zinc therapy on neutrophil chemotaxis in psoriasis. 1980;13(1):20-25. Effects of zinc in chronic hemodialysis. Bobat, R., Coovadia, H., Stephen, C., Naidoo, K. L., McKerrow, N., Black, R. E., and Moss, W. J. View abstract. Taking zinc by mouth improves symptoms of an inherited disorder called Wilson disease. J Health Popul.Nutr. Ind J Gastroenterol 2002;21:216-8. Cancer of the white blood cells (leukemia). 2007;60(6):560-566. (Accessed: 4/12/2017). View abstract. View abstract. Am J Clin Nutr 1998;68:365-71. Physiol Behav 1993;53:587-92. Al-Bader, A., Omu, A. E., and Dashti, H. Chronic cadmium toxicity to sperm of heavy cigarette smokers: immunomodulation by zinc. Esmaeli, B., Burnstine, M. A., Martonyi, C. L., Sugar, A., Johnson, V., and Brewer, G. J. Regression of Kayser-Fleischer rings during oral zinc therapy: correlation with systemic manifestations of Wilson's disease. Arch Intern Med 1999;159:748-54. View abstract. Inter-relationship of zinc levels in serum and semen in oligospermic infertile patients and fertile males. Lipid peroxidation in insulin-dependent diabetic patients with early retina degenerative lesions: effects of an oral zinc supplementation. Zinc sulphate for acute bronchiolitis: A double-blind Am J Hematol 1999;61:194-202. Int Urol Nephrol 1997;29:565-74. Lukacik, M., Thomas, R. L., and Aranda, J. V. A meta-analysis of the effects of oral zinc in the treatment of acute and persistent diarrhea. View abstract. Taking zinc does not seem to be linked to the risk of getting prostate cancer. View abstract. Lovell MA, Robertson JD, Teesdale WJ, et al. Freeland-Graves JH, Lin PH. J Drugs Dermatol 2005;4(1):73-79. View abstract. High dietary calcium intakes reduce zinc absorption and balance in humans. Dreno B, Amblard P, Agache P, et al. Clin Exp Dermatol 1997;22:169-73. Simonart, T. and de, Maertelaer, V. Systemic treatments for cutaneous warts: a systematic review. Zumkley H, Bertram HP, Preusser P, et al. View abstract. View abstract. View abstract. View abstract. Early research suggests that applying a zinc sulfate solution improves plane warts but not common warts. Fleet JC, Turnbull AJ, Bourcier M, Wood RJ. Cohanim M, Yendt ER. 2016;11(11):e0165956. Hustead, V. A., Greger, J. L., and Gutcher, G. R. Zinc supplementation and plasma concentration of vitamin A in preterm infants. Von Hoff DD. Omu AE, Dashti H, Al-Othman S. Treatment of asthenozoospermia with zinc sulphate: andrological, immunological and obstetric outcome. 1993;69(1):243-255. Acta Med Scand 1980;208:209-12. View abstract. Itching. View abstract. Dietary interventions to prevent zinc deficiency. A. 1997;55(3):82-85. Available from: URL: http://ods.od.nih.gov/factsheets/Zinc-HealthProfessional/" ([cited 2012]): 2. Fatty acid composition of plasma lipids in acrodermatitis enteropathica before and after zinc supplementation. Int Dent J. View abstract. Failure of zinc gluconate in treatment of acute upper respiratory tract infections. View abstract. Multivitamin use and risk of prostate cancer in the National Institutes of Health-AARP Diet and Health Study. Personal communication: Pantoprazole IV - safety and tolerability of EDTA. A., Lewin, S. R., Wightman, F., Lee, M., Ravindran, T. S., and Paton, N. I. Li Z, Li B, Song X, Zhang D. Dietary zinc and iron intake and risk of depression: A meta-analysis. Meynadier J. Efficacy and safety study of two zinc gluconate regimens in the treatment of inflammatory acne. Friis, H., Ndhlovu, P., Mduluza, T., Kaondera, K., Sandstrom, B., Michaelsen, K. F., Vennervald, B. J., and Christensen, N. O. Pediatrics 2003;112(6 Pt 1):1327-1332. Zinc is an essential trace element involved in most major metabolic pathways. Treatment of Wilson disease with ammonium tetrathiomolybdate. "Product Information. J Reprod Med 1984;29:547-50.. View abstract. J Nutr 2000;130:1488S-92S. Arad, A., Mimouni, D., Ben Amitai, D., Zeharia, A., and Mimouni, M. Efficacy of topical application of eosin compared with zinc oxide paste and corticosteroid cream for diaper dermatitis. O'Brien KO, Zavaleta N, Caulfield LE, et al. View abstract. Early research suggests that taking zinc can improve immune function and reduce infections in people with Down syndrome who are zinc deficient and have weakened immune systems. Zeng, L. and Zhang, L. Efficacy and safety of zinc supplementation for adults, children and pregnant women with HIV infection: systematic review. Zarembo JE, Godfrey JC, Godfrey NJ. Effect of vitamin A and zinc supplementation on gastrointestinal parasitic infections among Mexican children. J Am Coll Nutr 1995;14:364-8. Aydinok Y, Coker C, Kavakli K, et al. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. 1981;70(5):1001-1004. For leg ulcers: 220 mg of zinc sulfate taken three times daily has been used along with ulcer dressings. Zinc metabolism in non-insulin dependent diabetes mellitus. Acta Derm Venereol Suppl (Stockh) 1990;154:1-36. View abstract. Evaluation of oral zinc sulfate effect on obsessive-compulsive disorder: a randomized placebo-controlled clinical trial. Smith W, Mitchell P, Webb K, Leeder SR. Dietary antioxidants and age-related maculopathy: the Blue Mountains Eye Study. O'Brien KO, Zavaleta N, Caulfield LE, et al. Effect of micronutrient supplementation on infection in institutionalized elderly subjects: a controlled trial. Prasad AS, Oberleas D, Lei KY, et al. Pol.J Pharmacol. Increased intake of zinc has been linked to a 17% to 20% reduced risk of colon and rectal cancer. In most instances, the better that a mineral is absorbed, the fewer the side effects, which are often GI symptoms such as constipation or diarrhea. Am J Med 2001;111:103-8. Zinc supplementation might potentiate the effect of vitamin A in restoring night vision in pregnant Nepalese women. J Periodontol 1990;61:674-9. Biol.Trace Elem.Res 1993;39(2-3):171-175. 2010;72(3):220. Brain tumor. View abstract. We comply with the HONcode standard for trustworthy health information -, Vitamin/Mineral Supplementation and Deficiency. 'S disease ( hepatollenticular degeneration ) function in people with a rare type of advanced nose throat... 2 to 59 months of age the body releases used as a result zinc. Oral ethinyl oestradiol and norethisterone on plasma levels a and zinc in ulcerative colitis.! Fisher: zinc for treating diarrhoea in children with acute diarrhea in Pakistan, Desai,. 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