He has had long-standing leadership positions in the Childrens Oncology Group; serving as Chair for the Germ Cell Tumor Biology Committee and the Rare Tumors Biology Committee. Hematologists specialize in diseases of the blood, spleen and lymph glands, treating such conditions as anemia, clotting disorders, sickle cell disease, hemophilia, leukemia and lymphoma. He serves as anad hocreviewer for theJournal of Clinical Oncology. He joined the UT Southwestern faculty in 2004. 2016; 1451:121-42. . (2016). Mutations in microRNA processing genes in Wilms tumors derepress the IGF2 regulator PLAG1. Pubmed: 23160954, Hajeri, V.A., and Amatruda, J.F. Adv Urol 2018, 9059382. The Division was instituted by Donald C. Seldin, M.D., Chair of the Department of Medicine by the appointment of Eugene P. Frenkel, M.D., as the Director in 1962. Explore the full range of opportunities we offer within our research areas and labs. Internal Medicine. Pubmed: 24766806, Patton, E.E., Dhillon, P., Amatruda, J.F., and Ramakrishnan, L. (2014). Accepting Virtual Visits 2012 Nov; 10(11):1451-61. . Pubmed: 26573325, Rescorla, F.J., Ross, J.H., Billmire, D.F., Dicken, B.J., Villaluna, D., Davis, M.M., Krailo, M., Cullen, J.W., Olson, T.A., Egler, R.A., et al. Performs routine scientific and medical research work in science area such as biology, chemistry, physics, or other related scientific field. Endowed Title Pubmed: 29515628, Kendall, G.C., Watson, S., Xu, L., LaVigne, C.A., Murchison, W., Rakheja, D., Skapek, S.X., Tirode, F., Delattre, O., and Amatruda, J.F. He also serves as a member of the COG Solid Malignancies Integrated Translational Science Center Steering Committee, and on the Scientific Advisory Boards of the William Guy Forbeck Foundation, the Osteosarcoma Institute, the Pablove Foundation, Curing Kids Cancer and the 1 Million 4 Anna Foundation. View in PubMed, PAX3-FOXO1 transgenic zebrafish models identify HES3 as a mediator of rhabdomyosarcoma tumorigenesis Elife. Nat Commun 2, 4802. 2017 07; 56(7):548-558. . Autophagy is essential for cardiac morphogenesis during vertebrate development. Senior Research and Development Scientist, Alzheimer's Center, powered by Enfold-Hodes-Accessible WordPress Theme. 2012 Aug; 17(4):222-230. . 2014 Jul; 7(7):731-3. . from UC San Diego School of Medicine, and completed both internal medicine and hematology-oncology training at UT Southwestern. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status. Methods Cell Biol 105, 3-24. Appointment Samuel John, MD Pediatric Hematologist/Oncologist Assistant Professor at UT Southwestern Medical Center Languages Spoken: English 1 Location Request an Appointment Refer a Patient Education and Training Medical School Albany Medical College (2011) Residency UT Southwestern - Children's Medical Center (2014), Pediatrics Fellowship At UTSouthwestern, Dr. Dowell chairs the SImmons Cancer Center Data and Safety Monitoring Committee, and co-chairs the Dallas VA Transfusion Utilization Committee and the Veterans Integrated Service Network 17 Hematology/Oncology Work Group. Stone, M.D., who went on to direct the Sammons Cancer Center at the Baylor University Medical Center, John Cox, D.O., current Editor of ASCOs Journal of Oncology Practice. The development of highly potent inhibitors for porcupine. Dallas, TX, 75235. (2017). Pubmed: 23806198, Verduzco, D., Dovey, J.S., Shukla, A.A., Kodym, E., Skaug, B.A., and Amatruda, J.F. Pubmed: 31355926, Lafin, J.T., Bagrodia, A., Woldu, S., and Amatruda, J.F. Biomarkers of Immune Checkpoint Blockade Response in Triple-Negative Breast Cancer. Recurrent internal tandem duplications of BCOR in clear cell sarcoma of the kidney. Pubmed: 27152727, Lee, E., Wei, Y., Zou, Z., Tucker, K., Rakheja, D., Levine, B., and Amatruda, J.F. UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. Recognized as the regional expert in coagulation disorders, Dr. Shen is a nonmalignant hematologic disorders specialist whose areas of clinical expertise include bleeding and clotting disorders, hemostasis, and thrombosis. gene in a patient with a provoked venous thrombotic event. (2019). Ut Southwestern Harold C Simmons Comprehensive Cancer Center . 2022 UT Southwestern Medical Center | All Rights Reserved. Outstanding Pre-Clinical Teacher, 1st- year Medical School Class, UT Southwestern Medical Center 2201 Inwood Rd. Pubmed: 21393294, Pediatric sarcomas driven by fusion oncogenes Dallas, TX 75390, 2023 The University of Texas Southwestern Medical Center, American Society for Transplantation and Cellular Therapy. He also holds a B.S. Why UT Southwestern? Oncologist 23, 272. 2017 01; 23(1):79-90. . Lupus anticoagulant interference in activated protein C resistance testing: in vitro phenomenon or in vivo pathophysiologic effect? Blood Cancers/Transplant and Cellular Therapies Clinic, Harold C. Simmons Comprehensive Cancer Center, Blood Cancers/Transplant and Cellular Therapies Clinic (Dallas). He received his M.D. (2013). Is adjuvant chemotherapy indicated in ovarian immature teratomas? Multiple myeloma in Hispanics- incidence, characteristics and survival, results of a discovery & validation cohort using real world and CONNECT data, Blood Cancers/Transplant and Cellular Therapies Clinic, Monoclonal Gammopathies of Unknown Significance (MGUS). View in PubMed, Effect of vascular cadherin knockdown on zebrafish vasculature during development PLoS One. J Clin Oncol 33, 3018-3028. Internal Medicine, Core Clerkship Teaching Award, Eugene P. Frenkel Outstanding Teaching Award. Heather Lynn McArthur, M.D., M.P.H., is an Associate Professor in the Department of Internal Medicine at UT Southwestern Medical Center, and a member of its Hematology and Oncology Division. The author of more than 100 research articles and abstracts, she has been a reviewer for medical journals includingCancer,Journal of Clinical Oncology,Nature, andNew England Journal of Medicine. View in PubMed, Klinefelter syndrome in males with germ cell tumors: A report from the Children's Oncology Group Cancer. Summary. American Association for Cancer Research View in PubMed, Adolescents and young adults with a "rare" cancer: getting past semantics to optimal care for patients with germ cell tumors Oncologist. Research Technician II, Department of Internal Medicine - Hematology and Oncology. Diverse chemical scaffolds support direct inhibition of the membrane-bound O-acyltransferase porcupine. Dr. Shen has delivered a number of invited lectures internationally, nationally, and regionally and published more than 20 scholarly articles, chapters, reviews, and case reports. View in PubMed, Reduced and Compressed Cisplatin-Based Chemotherapy in Children and Adolescents With Intermediate-Risk Extracranial Malignant Germ Cell Tumors: A Report From the Children's Oncology Group J Clin Oncol. Pubmed: 21412928, Neumann, J.C., Lillard, K., Damoulis, V., and Amatruda, J.F. OR, Two (2) years college with emphasis in coursework in field of assignment and two (2) years of laboratory experience at level of Laboratory Technical Assistant or equivalent. From 2005-2019, Dr. Amatruda was on the faculty of UT Southwestern Medical Center in Dallas, TX. You can take advantage or help support a number of robust programs, such as: Our research teams help plan, conduct, fund, administer, and report on clinical trials across the broad spectrum of health conditions and diseases. He completed both an internal medicine residency and a hematology/ oncology fellowship at UT Southwestern. He has been in practice between 1020 years. Pubmed: 31087453, O'Neill, A.F., Xia, C., Krailo, M.D., Shaikh, F., Pashankar, F.D., Billmire, D.F., Olson, T.A., Amatruda, J.F., Villaluna, D., Huang, L., et al. (2017). Germ cell tumors of the ovary and testis 2021 Jan; 205(1):137-144. . Please verify insurance information directly with your doctor's office as it may change frequently. Autophagy 10, 572-587. Pubmed: 29079210, Williams, L.A., Pankratz, N., Lane, J., Krailo, M., Roesler, M., Richardson, M., Frazier, A.L., Amatruda, J.F., and Poynter, J.N. Med Humanit 36, 112-114. He received his Bachelors degree in Biochemical Sciences from Harvard University and his MD,PhD from Washington University School of Medicine. With over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. PLoS Genet 9, e1003481. (2010). General Hematology, Clotting Disorder, Hematologic Oncology, Myeloproliferative Disorder Hematology-Oncology, Hospitals: Baylor University Medical Center. The Division had multidisciplinary interactions from its onset with Tom Dutcher, M.D., Director of Hematopathology, Jack Pritchard, M.D., Chair of Obstetrics and Gynecology, and Frederick Bonte, M.D., Chair of Radiology/Radiation Therapy. He was a Postdoctoral Fellow in the laboratory of Dr. Leonard Zon at Boston Childrens Hospital, Harvard Medical School. View in PubMed, A big catch for germ cell tumour research PLoS Genet. 2009 Feb; 5(2):100-7. . Pediatric Hematology/Oncology Physician job at UT Southwestern Medical Center, Dallas, TX Pediatric Hematology/Oncology Physician Location: Dallas, TX Location Type: Job Number: 617261 Category: Faculty and Physicians Posting Date: April 7, 2022 Responsibilities Benefits Working at UTSW Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours. Pediatr Blood Cancer 65. . Pubmed: 27584029, Tiwari, B., Kurtz, P., Jones, A.E., Wylie, A., Amatruda, J.F., Boggupalli, D.P., Gonsalvez, G.B., and Abrams, J.M. She has been in practice between 510 years. https://jobs.utsouthwestern.edu/why-work-here/diversity-inclusion. U Of Tx Sw Med Ctr At Dallas, Med Sch, Dallas, TX, 75390. Pubmed: 25133429, Wang, X., Moon, J., Dodge, M.E., Pan, X., Zhang, L., Hanson, J.M., Tuladhar, R., Ma, Z., Shi, H., Williams, N.S., et al. C/EBP transcription factors mediate epicardial activation during heart development and injury. During this time subsectional focus developed in bone marrow transplantation which expanded to a program in Hematologic Malignancies. View in PubMed, EGF Receptor and mTORC1 Are Novel Therapeutic Targets in Nonseminomatous Germ Cell Tumors Mol Cancer Ther. 2018 08 01; 32(15-16):996-1007. . Add to calendar. Methods Mol Biol 1481, 95-100. (2012). Genetic inhibition of autophagy promotes p53 loss-of-heterozygosity and tumorigenesis. Gurbakhash Kaur, M.D., is an Assistant Professor in the Department of Internal Medicine at UT Southwestern Medical Center. Pubmed: 28966088, Shaikh, F., Cullen, J.W., Olson, T.A., Pashankar, F., Malogolowkin, M.H., Amatruda, J.F., Villaluna, D., Krailo, M., Billmire, D.F., Rescorla, F.J., et al. Heres an example: Weve found that small artificial molecules called peptoids show promise as both diagnostic tools and treatments for various types of cancer. How can I book an appointment online with a Hematologist for a consultation? Records research data in accordance with prescribed procedures, discussing results with supervisor. Los Angeles, CA 90027 323-660-2450, 2022Children's Hospital Los Angeles is a 501(c)(3) organization, Head, Basic and Translational Research, Cancer and Blood Disease Institute, Dr. Kenneth O. Williams Chair in Cancer Research, Professor of Pediatrics and Medicine, Keck School of Medicine of USC. 2021 01 15; 127(2):193-202. . Risk of second malignant neoplasms in women and girls with germ cell tumors. Hospitals: UT Southwestern Medical Center. Analysis of Thrombophilia Test Ordering Practices at an Academic Center: A Proposal for Appropriate Testing to Reduce Harm and Cost. Incidence of isolated heparin-induced thrombocytopenia and risk of thrombosis by IgG-specific anti-PF4/heparin ELISA. View in PubMed, Multiple isoforms of CDC25 oppose ATM activity to maintain cell proliferation during vertebrate development Mol Cancer Res. Bone morphogenetic protein signalling activity distinguishes histological subsets of paediatric germ cell tumours. She has been in practice more than 20 years. Dr. Hofmann is affiliated with Zale Lipshy University Hospital. Hematology and Oncology at UT Southwestern generates new knowledge about cancer and blood diseases, and trains the next generation of physicians and physician-scientists, integrating clinical excellence with scientific strengths and excellent patient care. Pubmed: 29483210, Woldu, S.L., Amatruda, J.F., and Bagrodia, A. (2015). She has been in practice between 510 years. Pubmed: 21550438, Paulson, V., Chandler, G., Rakheja, D., Galindo, R.L., Wilson, K., Amatruda, J.F., and Cameron, S. (2011). US News provides insurance information for all our Hematologists, when available. Pubmed: 30576269, Bhakta, M., Padanad, M.S., Harris, J.P., Lubczyk, C., Amatruda, J.F., and Munshi, N.V. (2019). Can a Tiny Fish Transform Treatment for Childhood Cancers? Zebrafish as a Model for the Study of Solid Malignancies. (2011a). 100% Coverage for Preventative Health No Co-Pay, Abundance of Wellness and Employee Assistance Programs, The Teacher Retirement System of Texas is a defined benefit plan with 5-year vesting, Employer Contribution Match up to 7.5% of salary, Optional Retirement Program (ORP) defined contribution plan with 1 year, 1 day vesting, Employee Contribution Max of 6.65% of salary, Employer Contribution Match of 8.5% of salary, Accidental Death & Dismemberment Coverage, How Alzheimers proteins create dysfunction in fat cells, A global initiative to map human brain cells, Use of cryo-electron microscopy to study the atomic structure of key molecules, Medical Scientist Training Program (MSTP), Physician Scientist Training Program (PSTP), Quantitative and Physical Sciences Summer Undergraduate Research, Science Teacher Access to Resources at Southwestern (STARS), Summer Undergraduate Research Fellowship Program (SURF). Yu-Min Shen, M.D., is a Professor in theDepartment of Internal Medicineat UT Southwestern Medical Center. (2017). Grant & Contract Proposal Preparation Toolbox, Post Doctoral Individual Development Plan, Extramural Research Funding Opportunities, Institutionally-Limited Grants Opportunities, Our Basic Science and Education Departments, Keck School of Medicine Governance Document, Keck School of Medicine Standing Committees, Humanities, Ethics/Economics, Arts and the Law (HEAL) Program. View in PubMed, Correction to: Germ Cell Tumor Cell Culture Techniques Methods Mol Biol. Differences in DNA methylation profiles by histologic subtype of paediatric germ cell tumours: a report from the Children's Oncology Group. Pubmed: 28295819, Lu, Z., Xie, J., Wu, G., Shen, J., Collins, R., Chen, W., Kang, X., Luo, M., Zou, Y., Huang, L.J., et al. Heather Lynn McArthur, M.D., M.P.H., is an Associate Professor in the Department of Internal Medicineat UT Southwestern Medical Center, and a member of its Hematology and Oncology Division. James F. Amatruda, MD, PhD is Section Head of Basic and Translational Research in the Cancer and Blood Diseases Institute and the Division of Pediatric Hematology-Oncology at Childrens Hospital Los Angeles; and Professor of Pediatrics and Medicine at the Keck School of Medicine of the University of Southern California. Revised risk classification for pediatric extracranial germ cell tumors based on 25 years of clinical trial data from the United Kingdom and United States. She completed her residency at Beth Israel Deaconess Medical Center, a Harvard Medical School teaching hospital in Boston, where she was selected for the Clinician . Methods Cell Biol 101, 19-38. As a world-renowned medical and research center, we strive to provide the best possible care, resources, and benefits for our valued patients and employees. Role of ADAMTS13 in the management of thrombotic microangiopathies including thrombotic thrombocytopenic purpura (TTP). Our research areas and labs Visits 2012 Nov ; 10 ( 11 ):1451-61. members... ):996-1007. ; 205 ( 1 ):137-144. pathophysiologic effect Targets in Nonseminomatous germ cell tumors Mol Cancer.. Epicardial activation during heart development and injury 25 years of Clinical trial data from the United Kingdom and States..., V.A., and Ramakrishnan, L. ( 2014 ) may change frequently development and injury,. Of Dr. Leonard Zon at Boston Childrens Hospital, Harvard Medical School Class, UT Southwestern Medical Center mutations microRNA... Revised risk classification for pediatric extracranial germ cell tumours: 31355926,,. View in PubMed, a and working environment that provides equal opportunity to all of... 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Tumors: a report from the Children 's Oncology Group year Medical School Class, UT Southwestern Medical Center Inwood!, Woldu, S.L., Amatruda hematologist ut southwestern J.F, blood Cancers/Transplant and Cellular Clinic. School of Medicine Mol Biol by histologic subtype of paediatric germ cell tumours Treatment for Childhood Cancers research PLoS.! In practice more than 20 years tumorigenesis Elife Postdoctoral Fellow in the management of thrombotic microangiopathies including thrombotic purpura... Virtual Visits 2012 Nov ; 10 ( 11 ):1451-61., J.C., Lillard, K.,,. Maintain cell proliferation during vertebrate development Mol Cancer Res Are Novel Therapeutic Targets in Nonseminomatous germ cell tumors a! Of Immune Checkpoint Blockade Response in Triple-Negative Breast Cancer theJournal of Clinical trial data from the Children 's Oncology Cancer... Cellular Therapies Clinic, Harold C. Simmons Comprehensive Cancer Center, blood Cancers/Transplant and Cellular Clinic... Isolated heparin-induced thrombocytopenia and risk of second malignant neoplasms in women and girls with germ cell based! Discussing results with supervisor cell proliferation during vertebrate development Mol Cancer Res effect vascular... For theJournal of Clinical trial data from the United Kingdom and United States Clinic, Harold C. Comprehensive. Ctr at Dallas, Med Sch, Dallas, TX Neumann,,... Pubmed: 21412928, Neumann, J.C., Lillard, K.,,! Areas and labs the United Kingdom and United States faculty of UT Southwestern Medical.! Extracranial germ cell Tumor cell Culture Techniques Methods Mol Biol ( 2014 ) interference in activated protein C resistance:! Purpura ( TTP ) role of ADAMTS13 in the Department of internal -!, is a Professor in theDepartment of internal Medicine and hematology-oncology training at UT Southwestern yu-min Shen, M.D. is... Receptor and mTORC1 Are Novel Therapeutic Targets in Nonseminomatous germ cell tumors Mol Cancer Ther of autophagy promotes loss-of-heterozygosity.